Fiorentina look to Nico Gonzalez, Andrea Belotti and Lucas Beltran in this head-to-head for Europe with Ciro Immobile and Felipe Anderson’s Lazio.
It kicks off at the Stadio Artemio Franchi at 19.45 GMT.
Only two points separate these teams going in, as Lazio are fresh from Thursday’s 2-0 win away to Torino, rescheduled from January due to the Supercoppa Italiana.
The Viola were fourth only a few weeks ago, but have really struggled in 2024 with only one win, two draws and four defeats in Serie A, as well as a 3-0 Supercoppa defeat to Napoli.
Lucas Martinez-Quarta is out with a muscular issue, joining Dodo, Oliver Christensen and Gaetano Castrovilli on the treatment table.
Christian Kouame was taken into hospital this week after contracting malaria during AFCON, but has been released to recuperate at home.
After those dismal recent outings, Vincenzo Italiano was reported to be considering a return to 4-3-3, but it remains the 4-2-3-1 with Giacomo Bonaventura coming back into midfield.
Lazio have Mario Gila suspended after his red card with Torino, plus Gil Patric and Nicolò Rovella injured.
Nicolò Casale was struggling with flu symptoms, while Matias Vecino and Mattia Zaccagni are only fit enough for the bench after their lay-offs.
Fiorentina have a remarkably poor record against Lazio, winning just one of their last 14 competitive meetings, losing 10 of them.
This is also the first match with the Curva Ferrovia section of the Stadio Franchi closed for restructuring work, reducing capacity to 30,000.
Fiorentina: Terracciano; Kayode, Milenkovic, Ranieri, Biraghi; Arthur, Bonaventura; Gonzalez, Beltran, Sottil; Belotti
Lazio: Provedel; Lazzari, Casale, Romagnoli, Marusic; Guendouzi, Cataldi, Luis Alberto; Isaksen, Immobile, Felipe Anderson
Player statistic
| 45' |  |
Luis Alberto (Assist: Mattéo Guendouzi) |
| Michael Kayode | |
61' | ||
| Nico González |  |
67' | ||
| 67' |  |
Mattéo Guendouzi | ||
| Giacomo Bonaventura | |
69' | ||
| 88' | |
Matías Vecino |
Match statistic
