Inter rely on Romelu Lukaku, Joaquin Correa and Hakan Calhanoglu in the trip to Empoli, a side that already beat them this season, as the race is on to get back into the top four.
It kicks off at the Stadio Castellani at 11.30 UK time (10.30 GMT).
You can follow all the build-up and action from today’s five Serie A games on the LIVEBLOG.
The Nerazzurri are in the semi-finals of the Champions League and the Coppa Italia, but were already struggling in Serie A and the verdict returning Juventus their 15 points has pushed them down to sixth place.
Milan Skriniar is probably out for the rest of the season after back surgery, while Henrikh Mkhitaryan has not made the trip due to personal reasons.
Simone Inzaghi rotates the squad after the 3-3 draw with Benfica, desperate to turn around the recent Serie A record of one point from the last five rounds.
Empoli were able to hold Milan to a 0-0 draw last week, but followed that up with a surprise defeat to Cremonese.
Koni De Winter, Guglielmo Vicario and Jean-Daniel Akpa Akpro are on the treatment table.
Empoli: Perisan; Ebuehi, Ismajli, Luperto, Parisi; Haas, Marin, Bandinelli; Baldanzi; Caputo, Cambiaghi
Inter: Handanovic; D’Ambrosio, De Vrij, Acerbi; Bellanova, Gagliardini, Brozovic, Calhanoglu, Gosens; Lukaku, Correa
Player statistic
Fabiano Parisi | 32' |
48' | Romelu Lukaku (Assist: Marcelo Brozovic) | |||
76' | Romelu Lukaku (Assist: Hakan Calhanoglu) | |||
81' | Nicolò Barella | |||
88' | Lautaro Martínez (Assist: Romelu Lukaku) |