Juventus hope to start 2023 the way they closed out the last year, but with Angel Di Maria and Dusan Vlahovic out, it’s Arkadiusz Milik who starts against Cremonese.
It kicks off at the Stadio Giovanni Zini at 17.30 GMT.
The Bianconeri ended 2022 in stunning form with six consecutive Serie A victories, which propelled them into third place, but the break for the World Cup has not been kind.
The injury list for this game includes Di Maria, Vlahovic, Leonardo Bonucci, Paul Pogba, Mattia De Sciglio, Juan Cuadrado and Kaio Jorge.
Milik therefore leads the way with support from youth team players Fabio Miretti, Matias Soulé and Nicolò Fagioli.
Cremonese are still without a Serie A victory since their promotion last summer, but have stuck with coach Massimiliano Alvino.
Vlad Chiriches, Ionut Radu and Christian Acella are out of action, as David Okereke and Cyriel Dessers start upfront.
Cremonese: Carnesecchi; Ferrari, Bianchetti, Lochosvili; Pickel, Castagnetti, Sernicola, Valeri, Meite; Okereke; Dessers
Juventus: Szczesny; Gatti, Bremer, Danilo; Soulé, Fagioli, Locatelli, McKennie, Kostic; Miretti; Milik