Enzo Barrenechea could make his debut as a starter for Juventus in the Derby Della Mole, while Ivan Ilic is tipped to start in the Granata’s midfield.
It kicks off at 19.45 GMT on Tuesday.
The Bianconeri are without the injured Arek Milik and Fabio Miretti, while Manuel Locatelli is suspended. Barrenechea, a 21-year-old midfielder from Juventus’ NextGen squad, could replace the Italy international in the middle of the park with Leandro Paredes initially on the bench.
Federico Chiesa and Paul Pogba are available but not expected to start.
Torino boss Ivan Juric must cope without David Zima, Ronaldo Vieira, Valentino Lazaro, Nikola Vlasic and Pietro Pellegrini. Ola Aina is suspended.
Michel Adopo or Karol Linetty will partner with Ivan Ilic in the middle of the park, while Ricardo Rodriguez is expected to start as a left wing-back.
The last time Torino won a derby away was in 1995, while Juventus have only lost one of the last 33 matches against the Granata and are unbeaten in the last 17 games across all competitions against their city rivals.
Juventus vs. Torino – probable line-ups
Juventus (3-5-2): Szczesny; Danilo, Bremer, Alex Sandro; Cuadrado, Fagioli, Barrenechea, Rabiot, Kostic; Vlahovic, Di Maria.
Torino (3-4-2-1): Milinkovic-Savic; Djidji, Schuurs, Bungiorno; Singo, Ilic, Adopo, Rodriguez; Miranchuk, Karamoh; Sanabria.