Nico Gonzalez and M’Bala Nzola start for Fiorentina in the Tuscan derby against Empoli at the Stadio Franchi.
It kicks off at 19:45 BST.
The Viola are without the injured Cristiano Biraghi and Dodo so Michael Kayode and Fabiano Parisi start as right and left-back respectively.
A win would allow Fiorentina to catch Juventus in third with 20 points, two below Serie A leaders Inter.
Empoli star Tommaso Baldanzi starts on the bench after playing and scoring in Italy U21’s 2-0 win over Norway last week.
The Azzurri boss Aurelio Andreazzoli looks to Nicolò Cambiaghi, Matteo Cancellieri and Francesco Caputo in attack.
Fiorentina-Empoli: confirmed line-ups
Fiorentina (4-3-3): Terracciano; Kayode, Milenkovic, Martinez Quarta, Parisi; Arthur, Duncan; Nico Gonzalez, Bonaventura, Brekalo; Nzola.
Empoli (4-3-3): Berisha; Ebuehi, Walukiewicz, Luperto, Cacace; Maleh, Marin, Grassi; Cancellieri, Caputo, Cambiaghi.