Napoli travel to Sassuolo with a revamped defence, as new coach Rino Gattuso hopes to ends 2019 with his first victory, while Domenico Berardi is a doubt.
It kicks off at 19.45 GMT, click here for a match preview.
The Partenopei are without Kalidou Koulibaly and Nikola Maksimovic, both of whom are injured. The Serbian defender is also serving a suspension after getting sent off for dissent against Udinese, despite being on the bench.
Napoli travel to Sassuolo with a revamped defence, as new coach Rino Gattuso hopes to ends 2019 with his first victory, while Domenico Berardi is a doubt.
It kicks off at 19.45 GMT, click here for a match preview.
The Partenopei are without Kalidou Koulibaly and Nikola Maksimovic, both of whom are injured. The Serbian defender is also serving a suspension after getting sent off for dissent against Udinese, despite being on the bench.
This means Sebastiano Luperto should play alongside Kostas Manolas in central defence.
Gattuso will continue to implement the 4-3-3 system that had been discarded by former boss Carlo Ancelotti during his time at the club.
The midfield three is expected to be Allan in the middle flanked by Fabian Ruiz and Piotr Zielinski.
Jose Callejon and Lorenzo Insigne can play either side of Arkadiusz Milik in attack for Napoli, leaving Dries Mertens on the touchline.
Sassuolo meanwhile are without goalkeeper Andrea Consigli, striker Gregoire Defrel and Vlad Chiriches through injury.
Right-back Jeremy Toljan is suspended, so 20-year-old Turkey international Mert Muldur steps in.
Berardi is also a slight doubt after picking up a knock in training, although it is believed he will still play.
Roberto De Zerbi will continue with the 4-2-3-1 system that he believes unlocks the best characteristics of his side.
Probable line-ups:
Sassuolo (4-2-3-1): Pegolo; Muldur, Romagna, Ferrari, Kyriakopoulos; Magnanelli, Locatelli; Berardi, Djuricic, Boga; Caputo.
Napoli (4-3-3): Meret; Di Lorenzo, Manolas, Luperto, Mario Rui; Allan, Fabian, Zielinski; Callejon, Milik, Insigne
Ref: Chiffi