Milan are expected to start with Rafael Leao up front, while Fikayo Tomori should get the nod at the back against Red Star Belgrade.
The match kicks off at 20.00 UK time.
The Rossoneri returned from Serbia with a 2-2 draw and Stefano Pioli will rely on Leao in the decisive leg at San Siro.
Zlatan Ibrahimovic will be rested for Sunday and Tomori should partner captain Alessio Romagnoli in the heart of the defence.
Gigio Donnarumma is certain in goal, with Davide Calabria and Theo Hernandez completing the home side’s back-four.
Milan are expected to start with Rafael Leao up front, while Fikayo Tomori should get the nod at the back against Red Star Belgrade.
The match kicks off at 20.00 UK time.
The Rossoneri returned from Serbia with a 2-2 draw and Stefano Pioli will rely on Leao in the decisive leg at San Siro.
Zlatan Ibrahimovic will be rested for Sunday and Tomori should partner captain Alessio Romagnoli in the heart of the defence.
Gigio Donnarumma is certain in goal, with Davide Calabria and Theo Hernandez completing the home side’s back-four.
Soualiho Meite is expected to start next to Franck Kessie in the middle, leaving Sandro Tonali out of the line-up, while Samu Castillejo, Rade Krunic and Hakan Calhanoglu should play in an attacking trident behind Leao.
Dejan Stankovic has been forced to leave out Milan Rodic, who is suspended and will most likely be replaced by Milan Gajic.
The Serbians arrive in a 3-4-2-1 formation and Italian Diego Falcinelli is expected to start up front tonight.
Milan (probable): Donnarumma; Calabria, Tomori, Romagnoli, Hernandez; Meite, Kessie; Castillejo, Krunic, Calhanoglu; Leao
Red Star (probable): Borjan; Pankov, Milunovic, Degenec; Gobeljic, Kanga, Petrovic, Gajic; Ben Nabouhane, Ivanovic; Falcinelli
Referee: Gil Manzano (ESP)