Napoli and Juventus plan big changes

Juventus are leaning towards a 3-5-2 formation with Mattia De Sciglio and Dejan Kulusevski in the starting XI, while Napoli could give Andre Frank Anguissa his debut from the start.

The Serie A clash kicks off at the Stadio Diego Armando Maradona on Saturday at 17.00 UK time (16.00 GMT).

Both teams have huge problems caused by injuries and the late arrival back from international duty of their South American players.

Max Allegri has opted to leave them behind in Turin along with injured Federico Chiesa, Arthur Melo and Kaio Jorge.

That rules out Juan Cuadrado, Paulo Dybala, Alex Sandro, Danilo and Rodrigo Bentancur.

While Moise Kean was a candidate to throw into the mix upfront, especially after his brace for Italy in the 5-0 win over Lithuania, it seems as if Dejan Kulusevski is favourite to partner Alvaro Morata.

Allegri is expected to shift onto a 3-5-2 formation, using De Sciglio and Pellegrini as the wing-backs, although Federico Bernardeschi is also an alternative on the left.

Napoli have problems too, as Piotr Zielinski, Diego Demme and Stanislav Lobotka are unlikely to feature, so ex-Fulham midfielder Anguissa could get his debut from the start in midfield.

Alex Meret is out with a back injury and David Ospina rushing back from Colombia to be fit in goal.

There was some good news for Luciano Spalletti today, as Dries Mertens and Faouzi Ghoulam trained with the full squad.

The Belgium international also stayed behind after the session to do some extra running work, hoping to get back to full fitness as soon as possible.

Victor Osimhen is available after his two-match ban for a reaction foul was halved on appeal and Lorenzo Insigne can start, having left the Italy camp early due to personal reasons.

Probable line-ups

Napoli: Ospina; Di Lorenzo, Manolas, Koulibaly, Mario Rui; Fabian Ruiz, Anguissa; Politano, Elmas, Insigne; Osimhen

Juventus: Szczesny; De Ligt, Bonucci, Chiellini; De Sciglio, McKennie, Locatelli, Rabiot, Pellegrini; Morata, Kulusevski