According to the latest reports, Simon Kjaer will return in defence for Milan against Monza, while Tommaso Pobega is preferred to Yunus Musah.
It kicks off at San Siro on Sunday at 11.30 GMT.
The Rossoneri are coming off a 2-1 Champions League victory away to Newcastle United, which was not enough to keep them in the competition, but does guarantee a spot in the Europa League knockout play-offs.
Stefano Pioli once again has serious problems to work around when putting together a starting XI.
Davide Calabria is suspended following his red card, while Malick Thiaw, Mattia Caldara, Pierre Kalulu, Marco Pellegrino and Marco Sportiello are injured.
There are suggestions that Musah is also struggling with a muscular issue, so Pobega was tested out in training.
The good news is that Kjaer finally returns after a long lay-off and is ready to start, allowing Theo Hernandez to return to his favoured left-back role and shifting Alessandro Florenzo to the right.
Olivier Giroud faces competition from Luka Jovic for the centre-forward slot.
Probable line-up
Milan (4-3-3): Maignan; Florenzi, Kjaer, Tomori, Theo Hernandez; Loftus-Cheek, Reijnders, Pobega; Pulisic, Giroud, Leao