Roma visit Spezia tomorrow without Sergio Oliveira or Felix Afena-Gyan, while Nicolò Zaniolo is expected to be on the bench, but there is some good news in defence.
The game kicks off on Sunday at 17.05 GMT.
Although a full squad has not been announced, the media watching the players get on the plane in Rome spotted several people were missing.
Among them, midfielder Oliveira and youth team striker Felix due to muscular problems, although defender Roger Ibanez was present after a month out injured.
It is a further blow to Jose Mourinho, who already had to do without Stephan El Shaarawy, Henrikh Mkhitaryan, Leonardo Spinazzola and Eldor Shomurodov.
Meanwhile, it’s reported Zaniolo will only be ready for a spot on the bench.
At least Gianluca Mancini returns from suspension to bolster the options at the back after missing the 2-2 thriller with Hellas Verona.
Roma have played three consecutive Serie A stalemates against Genoa, Sassuolo and Verona.
.@OfficialASRoma, contro lo @acspezia non ci saranno #SergioOliveira e #Felix: torna tra i convocati #Ibanezhttps://t.co/l5jjTsGTdk
— Gianluca Di Marzio (@DiMarzio) February 26, 2022