The centre-back has a release clause in his contract that is worth €125m this summer, rising to €140m in June 2023.
He has made comments suggesting that he is not happy with the level of ambition at the club, having finished fourth in Serie A for two years in a row.
Discussions over a contract extension have also hit problems, fuelling reports De Ligt could be sold over the next few months.
Sky Sport Italia transfer expert Gianluca Di Marzio claims that Chelsea have made an approach for the Dutch international.
Now Sportitalia via Alfredo Pedullà maintain Manchester City have also stepped forward with a proposal for De Ligt.
Neither of them are so far prepared to get close to the €125m release clause, but Juve may well take it into consideration if the offer reaches €100m.
The Bianconeri paid €85.5m to sign De Ligt from Ajax in 2019.
Alle 23 a #sportitaliamercato
📌 Pimenta a Milano: non solo Pogba, il City pensa a De Ligt
📌 Svincolati: Dybala, Di Maria, Belotti, Dembele…
📌 Roma, Pinto a Milano accende il mercato giallorosso
— Sportitalia (@tvdellosport) June 23, 2022