Join us for all the build-up and action as it happens from the Europa and Conference League, where Lazio seek revenge on Midtjylland, Fiorentina face leaders Istanbul Basaksehir and Roma must win away to HJK Helsinki.
We begin with two matches at 17.45 UK time (16.45 GMT).
Lazio are flying high in Serie A, but that form has not translated to the Europa League so far in a ridiculously balanced group with all four teams on five points.
They host Midtjylland, eager to avenge the shock 5-1 defeat in Denmark even without injured Ciro Immobile.
In the Conference League, Fiorentina need a victory against Istanbul Basaksehir to guarantee progress to the play-offs and that would take them joint top of the group too.
At 20.00 UK time (19.00 GMT), Roma risk early elimination from the Europa League if they don’t get a win away to HJK Helsinki, with Jose Mourinho already warning about the dangers of playing on an artificial pitch.
They are currently third in their group on just four points, while Ludogorets have seven and Betis 10.