It kicks off on neutral turf at the Mapei Stadium in Reggio Emilia at 20.00 UK time (19.00 GMT).
The Final will be decided after 90 minutes, extra time or even penalties, with the trophy lifted this evening.
Gian Piero Gasperini is aiming for the first piece of silverware in his tenure, the first for La Dea since the 1960s, and revenge after losing the Final to Lazio two years ago.
Today is Andrea Pirlo’s birthday and he hopes for his second Cup of the campaign, after winning the Supercoppa against Napoli in January.
Juventus have 13 editions of the Coppa Italia in their trophy cabinet, the most recent being in 2017-18.
Atalanta are unbeaten against Juve this season, managing a 1-1 draw in Turin and 1-0 home win, and will finish above the Old Lady.
There will be 4,300 fans in the stadium for the first time since the lockdown over a year ago.