Sassuolo hope Domenico Berardi and Matteo Politano can find the net as they host high-flying Atalanta, but Papu Gomez is on the bench.
It kicks off at 17.00 GMT, follow the build-up and action from this game and Chievo-Juventus on the LIVEBLOG.
The Neroverdi have been radically changed since Beppe Iachini replaced axed Coach Cristian Bucchi, earning three wins and two draws in their last seven games.
Sassuolo hope Domenico Berardi and Matteo Politano can find the net as they host high-flying Atalanta, but Papu Gomez is on the bench.
It kicks off at 17.00 GMT, follow the build-up and action from this game and Chievo-Juventus on the LIVEBLOG.
The Neroverdi have been radically changed since Beppe Iachini replaced axed Coach Cristian Bucchi, earning three wins and two draws in their last seven games.
Berardi ended his goal drought, but Politano is at the centre of a bidding war between Napoli and Juventus, so this could be his final appearance for Sassuolo.
Atalanta are still smarting after their controversial defeat to Napoli, as Coach Gian Piero Gasperini protested VAR was not used on an offside of a few centimetres.
Leonardo Spinazzola is out injured and hasn’t even made the trip, joined on the treatment table by January signing Luca Rizzo.
Captain Alejandro ‘Papu’ Gomez is not 100 per cent fit and won’t be risked from the start, as Atalanta face Juventus in the Coppa Italia semi-final on Tuesday.
That means Josip Ilicic is the support for Andreas Cornelius, again preferred to off-form Andrea Petagna.
There are several surprises from Gasperini, as Pierluigi Gollini is in goal with Rafael Toloi, Andrea Masiello and Timothy Castagne starting.
Atalanta are unbeaten against Sassuolo since a 2-0 defeat in Bergamo in April 2014, followed by four wins and four draws, home and away in all competition.
Sassuolo: Consigli; Lirola, Goldaniga, Acerbi, Peluso; Missiroli, Magnanelli, Duncan; Berardi, Falcinelli, Politano
Atalanta: Gollini; Toloi, Masiello, Palomino; Castagne, De Roon, Freuler, Gosens; Cristante; Ilicic, Cornelius