Napoli and Roma go head-to-head for a top four spot, with Dries Mertens, Lorenzo Insigne and Hirving Lozano against Edin Dzeko, Henrikh Mkhitaryan and Pedro.
It kicks off at 19.45 GMT, you can follow the build-up and action as it happens from all today’s Serie A games on the LIVEBLOG.
Napoli and Roma go head-to-head for a top four spot, with Dries Mertens, Lorenzo Insigne and Hirving Lozano against Edin Dzeko, Henrikh Mkhitaryan and Pedro.
It kicks off at 19.45 GMT, you can follow the build-up and action as it happens from all today’s Serie A games on the LIVEBLOG.
This is the Derby del Sud, traditionally a fiery clash between two rival sets of fans, but they were united this morning when Roma legend Bruno Conti visited the mural dedicated to his friend Diego Armando Maradona in the Spanish Quarter of Naples.
The Stadio San Paolo will soon be renamed after Maradona and there will be a minute’s silence before kick-off, as well as play stopping at the 10th minute to applaud the ultimate 10.
Napoli will wear a special edition jersey this evening that has blue and white stripes, reminiscent of Maradona’s Argentina shirt.
As for the match, Napoli are on 14 points and Roma 17, so a win would put the Giallorossi clear in second place behind only leaders Milan.
Victor Osimhen is still out after dislocating his shoulder, while Elseid Hysaj and Amir Rrahmani have COVID.
Tiemoue Bakayoko is suspended in midfield, so Diego Demme – named after Maradona – steps in with Fabian Ruiz.
Piotr Zielinski moves into a more advanced role with Lozano, Insigne and Mertens.
Roma have Edin Dzeko back after he recovered from COVID and are brimming with confidence after qualifying for the Europa League knockouts on Thursday.
Chris Smalling, Marash Kumbulla, Javier Pastore and Nicolò Zaniolo are still out, but Gianluca Mancini and Roger Ibanez return to bolster the defence with Bryan Cristante.
Lorenzo Pellegrini and Leonardo Spinazzola are also passed fit to start, with Jordan Veretout, Pedro and Mkhitaryan.
Napoli: Meret; Di Lorenzo, Manolas, Koulibaly, Mario Rui; Demme, Fabian Ruiz; Lozano, Zielinski, Insigne, Mertens
Napoli bench: Contini, Ospina, Malcuit, Elmas, Llorente, Maksimovic, Politano, Ghoulam, Petagna, Lobotka
Roma: Mirante; Mancini, Cristante, Ibanez; Karsdorp, Pellegrini, Veretout, Spinazzola; Pedro, Mkhitaryan; Dzeko
Roma bench: Farelli, Pau Lopez, Juan Jesus, Villar, Mayoral, Perez, Peres, Diawara, Feratovic, Providence, Calafiori
Ref: Di Bello