Napoli need a victory to keep up the pressure on leaders Juventus and host Genoa with Leonardo Pavoletti.
It kicks off at the Stadio San Paolo at 17.00 GMT, follow the build-up and action on our LIVEBLOG.
The Partenopei aim to remain within three points of Juve at the top of the table and continue their current good form.
Maurizio Sarri has a full squad to choose from, so Jose Callejon and Lorenzo Insigne support Gonzalo Higuain.
Napoli need a victory to keep up the pressure on leaders Juventus and host Genoa with Leonardo Pavoletti.
It kicks off at the Stadio San Paolo at 17.00 GMT, follow the build-up and action on our LIVEBLOG.
The Partenopei aim to remain within three points of Juve at the top of the table and continue their current good form.
Maurizio Sarri has a full squad to choose from, so Jose Callejon and Lorenzo Insigne support Gonzalo Higuain.
Jorginho plays in midfield, celebrating his maiden senior Italy call-up for friendlies against Spain and Germany.
Genoa are without Ezequiel Munoz and Cristian Ansaldi, the Argentine in hospital after a bout of appendicitis.
It’s a return to his old stomping ground for ex-Napoli striker Goran Pandev, who completes the attack with Pavoletti.
The centre-forward is making his first appearance since Feburary 6, when he suffered a thigh strain.
Napoli: Reina; Hysaj, Albiol, Koulibaly, Ghoulam; Allan, Jorginho, Hamsik; Callejon, Higuain, Insigne
Genoa: Perin; Izzo, Burdisso, De Maio; Laxalt, Rincon, Dzemaili, Rigoni, Gabriel Silva; Pandev, Pavoletti