Milan have Mario Balotelli back and host another side desperate for points, as Frosinone need a result to avoid relegation.
It kicks off at 14.00 UK time (13.00 GMT), follow the action from all today's Serie A games on the LIVEBLOG.
The Rossoneri have plummeted since Cristian Brocchi took over from Sinisa Mihajlovic, as an opening 1-0 win at Sampdoria was followed by a dismal home draw with Carpi and shock defeat to bottom of the table Verona.
Milan have Mario Balotelli back and host another side desperate for points, as Frosinone need a result to avoid relegation.
It kicks off at 14.00 UK time (13.00 GMT), follow the action from all today's Serie A games on the LIVEBLOG.
The Rossoneri have plummeted since Cristian Brocchi took over from Sinisa Mihajlovic, as an opening 1-0 win at Sampdoria was followed by a dismal home draw with Carpi and shock defeat to bottom of the table Verona.
Balotelli returns from suspension to partner misfiring Carlos Bacca, but M’Baye Niang, Giacomo Bonaventura and Andrea Bertolacci are still injured.
Mattia De Sciglio’s rare start against Verona was cut short by a cut to the face that required seven stitches, but he returns to try again and allows Luca Antonelli to rest after becoming a father yesterday.
Frosinone’s hopes of survival suffered a massive blow with their 2-0 home defeat to Palermo, but Roberto Stellone insists his team will not be “depressed” at San Siro.
Raman Chibsah is suspended with Danilo Soddimo sidelined, but Federico Dionisi and Daniel Ciofani are finally both fit to start in attack.
A big loss is goalkeeper Nicola Leali, who has flu, so ex-Inter shot-stopper Francesco Bardi gets his chance.
The only previous meeting between these sides was a 4-2 away victory for Milan.
Milan: Donnarumma; Abate, Alex, Romagnoli, De Sciglio; Kucka, Montolivo, Jose Mauri; Honda; Bacca, Balotelli
Frosinone: Bardi; M Ciofani, Russo, Ajeti, Crivello; Paganini, Gori, Sammarco, Kragl; Dionisi, D Ciofani