It’s set to be the most hotly-contested Rome Derby in decades, as Lazio and Roma go head-to-head for third place with attacking formations.
It kicks off at 19.45 UK time (18.45 GMT), follow the build-up and action as it happens on the LIVEBLOG.
The Giallorossi are fresh from a shock 3-0 victory over Barcelona, which wiped out the 4-1 first leg defeat and booked their spot in the Champions League semi-finals.
It’s set to be the most hotly-contested Rome Derby in decades, as Lazio and Roma go head-to-head for third place with attacking formations.
It kicks off at 19.45 UK time (18.45 GMT), follow the build-up and action as it happens on the LIVEBLOG.
The Giallorossi are fresh from a shock 3-0 victory over Barcelona, which wiped out the 4-1 first leg defeat and booked their spot in the Champions League semi-finals.
Eusebio Di Francesco debuted his three-man defence in that game and it was a revelation, so he sticks with it today as well.
Kostas Manolas has shaken off flu symptoms to start, but Alessandro Florenzi is still not well, so Bruno Peres steps in at right wing-back.
Radja Nainggolan and Patrik Schick support centre-forward Edin Dzeko, but Diego Perotti and Gregoire Defrel are injured.
Lazio’s confidence is shot after Thursday’s astonishing capitulation to RB Salzburg, as they had been 5-3 up on aggregate in Austria when conceding three goals in four minutes to crash out of the Europa League.
Simone Inzaghi has to do without injured Patric, but opts to start Felipe Anderson on his birthday alongside Capocannoniere Ciro Immobile.
Sergej Milinkovic-Savic and Lucas Leiva pull the midfield strings, leaving Luis Alberto on the bench.
This fixture has produced a record nine red cards from the last nine matches, dating back to April 2009 when Christian Panucci, Matuzalem and Philippe Mexes all received their marching orders in a typically tempestuous encounter.
Lazio: Strakosha; Luiz Felipe, De Vrij, Radu; Marusic, Parolo, Leiva, Milinkovic-Savic, Lulic; Felipe Anderson, Immobile
Lazio bench: Guerrieri, Vargic, Bastos, Caceres, Wallace, Lukaku, Basta, Murgia, Di Gennaro, Nani, Luis Alberto, Caicedo
Roma: Alisson; Manolas, Fazio, Juan Jesus; Bruno Peres, De Rossi, Strootman, Kolarov; Nainggolan, Schick; Dzeko
Roma bench: Skorupski, Jonathan Silva, Capradossi, Luca Pellegrini, Florenzi, Lorenzo Pellegrini, Gonalons, Gerson, Cengiz Under, Antonucci, El Shaarawy
Ref: Mazzoleni