Juventus use Douglas Costa with Cristiano Ronaldo and Gonzalo Higuain, as Fiorentina debut Igor with Patrick Cutrone and Federico Chiesa.
It kicks off in Turin at 11.30 GMT.
Juventus use Douglas Costa with Cristiano Ronaldo and Gonzalo Higuain, as Fiorentina debut Igor with Patrick Cutrone and Federico Chiesa.
It kicks off in Turin at 11.30 GMT.
Maurizio Sarri was under fire after the surprise 2-1 defeat to Napoli, their second loss of the league campaign, third in all competition.
The Bianconeri are still top of the table, even if their lead has been sliced to three points.
Miralem Pjanic is fit to start despite a bruised ankle, but Douglas Costa gets a surprise start with Gonzalo Higuain and Cristiano Ronaldo.
Danilo, Merih Demiral, Sami Khedira and Giorgio Chiellini are injured, so Juan Cuadrado faces his former club in this season’s role of right-back.
Fiorentina are still unbeaten in Serie A under coach Beppe Iachini, but were knocked out of the Coppa Italia midweek by Inter.
Nikola Milenkovic and Martin Caceres sit out bans, with Gaetano Castrovilli, Franck Ribery, new signings Alfred Duncan and Christian Kouame injured.
That means Iachini throws January transfer deadline day buy Igor straight into the starting XI, just two days after his move from SPAL was completed.
Patrick Cutrone is chosen as the partner to Federico Chiesa, with Dusan Vlahovic ready to come off the bench.
Juventus have only failed to score in one of their 30 competitive matches under Sarri and that was a 0-0 draw in Florence on September 14.
There was fog over the Allianz Juventus Stadium this morning, but it quickly dissipated.
Juventus: Szczesny; Cuadrado, Bonucci, De Ligt, Alex Sandro; Rabiot, Pjanic, Bentancur; Douglas Costa, Higuain, Ronaldo
Juventus bench: Buffon, Pinsoglio, De Sciglio, Rugani, Coccolo, Ramsey, Matuidi, Bernardeschi, Dybala
Fiorentina: Dragowski; Ceccherini, Pezzella, Igor; Lirola, Pulgar, Benassi, Ghezzal, Dalbert; Chiesa, Cutrone
Fiorentina bench: Terracciano, Brancolini, Badelj, Sottil, Agudelo, Venuti, Vlahovic, Terzic, Dalle Mura
Ref: Pasqua