Inter can go two points clear at the top tonight, so start Mauro Icardi, Stevan Jovetic and Adem Ljajic against Frosinone.
It kicks off at 19.45 GMT, follow the action as it happens and give your views on our LIVEBLOG.
Fiorentina and Roma were held to 2-2 draws this weekend and Napoli won 2-0 in Verona, so a victory would make Roberto Mancini’s men the new sole Serie A leaders.
Inter can go two points clear at the top tonight, so start Mauro Icardi, Stevan Jovetic and Adem Ljajic against Frosinone.
It kicks off at 19.45 GMT, follow the action as it happens and give your views on our LIVEBLOG.
Fiorentina and Roma were held to 2-2 draws this weekend and Napoli won 2-0 in Verona, so a victory would make Roberto Mancini’s men the new sole Serie A leaders.
Davide Santon and Nemanja Vidic are the only absentees, but Mancio transforms his team get again with a 4-2-3-1 system.
He said Jovetic and Icardi needed to play together in order to form a stronger partnership and they get a rare start, but with the Montenegrin hanging back in a supporting trio with Ljajic and Jonathan Biabiany.
Ivan Perisic is dropped with Geoffrey Kondogbia and Felipe Melo providing a solid midfield unit.
Frosinone are in their first ever Serie A campaign and had never previously been to San Siro, so this will be an emotional night for players and fans.
Striker Federico Dionisi is suspended with Aleksandar Tonev, Daniel Pavlovic and Raman Chibsah injured.
Chile international striker Nicolas Castillo therefore starts in attack with Daniel Ciofani.
Samuele Longo, who is on loan from Inter, is on the bench.
Inter: Handanovic; Nagatomo, Miranda, Murillo, Telles; Melo, Kondogbia; Biabiany, Jovetic, Ljajic; Icardi
Inter bench: Carrizo, Berni, Jesus, Palacio, Guarin, Montoya, Medel, Ranocchia, Gnoukouri, D'Ambrosio, Perisic, Brozovic
Frosinone: Leali; Rosi, Diakité, Blanchard, Crivello; Paganini, Gori, Sammarco, Soddimo; D Ciofani, Castillo
Frosinone bench: Zappino, Gomis, Frara, Gucher, Verde, Longo, M Ciofani, Carlini, Bertoncini