Cagliari have to reshuffle their defence amid an injury crisis, while Parma continue their push for potential European places with Gervinho.
It kicks off at the Sardegna Arena at 17.00 GMT.
You can follow all the action as it happens from this game and Atalanta v Milan on the LIVEBLOG.
Cagliari Coach Rolando Maran barely has a choice to make, as his squad is decimated and sliding towards the relegation zone.
Cagliari have to reshuffle their defence amid an injury crisis, while Parma continue their push for potential European places with Gervinho.
It kicks off at the Sardegna Arena at 17.00 GMT.
You can follow all the action as it happens from this game and Atalanta v Milan on the LIVEBLOG.
Cagliari Coach Rolando Maran barely has a choice to make, as his squad is decimated and sliding towards the relegation zone.
On the absentee list are Ragnar Klavan, Paolo Faragò, Fabrizio Cacciatore, Cyril Thereau, Walter Birsa, Lucas Castro and Alberto Cerri.
Darijo Srna and Filippo Romagna are only fit for the bench.
That means Fabio Pisacane is re-routed to centre-back, with Luca Pellegrini on loan from Roma on the left side of defence.
Leonardo Pavoletti and Joao Pedro are supported by Artur Ionita and Nicolò Barella.
Parma’s only real issue is with Matteo Scozzarella, so Leo Stulac returns in midfield, while Roberto Gagliolo is suspended and Federico Dimarco still out injured.
Massimo Gobbi therefore has to step in, despite not playing for three months.
Luca Siligardi gets the nod rather than Jonathan Biabiany, joining usual suspects Roberto Inglese and Gervinho.
Cagliari: Cragno; Padoin, Ceppitelli, Pisacane, Pellegrini; Deiola, Cigarini, Barella; Ionita; Joao Pedro, Pavoletti
Parma: Sepe; Iacoponi, Bastoni, Bruno Alves, Gobbi; Kucka, Stulac, Barillà; Gervinho, Inglese, Biabiany