Napoli use Dries Mertens, Lorenzo Insigne and Jose Callejon together in a difficult trip to Cagliari, a game that should guarantee goals.
It kicks off at 11.30 GMT, follow the build-up and action while giving your views on the Liveblog.
The Partenopei had a rough patch, but appear to be back on track with important victories over Inter and Benfica, allowing them to win their Champions League group for the first time.
Napoli use Dries Mertens, Lorenzo Insigne and Jose Callejon together in a difficult trip to Cagliari, a game that should guarantee goals.
It kicks off at 11.30 GMT, follow the build-up and action while giving your views on the Liveblog.
The Partenopei had a rough patch, but appear to be back on track with important victories over Inter and Benfica, allowing them to win their Champions League group for the first time.
Arkadiusz Milik is hoping to make his comeback from a torn ACL next month, but in the meantime Manolo Gabbiadini is sent to the bench.
Coach Maurizio Sarri instead relies on the ‘light’ trident attack of Callejon, Mertens and Insigne, whose pace should cause big problems for Cagliari.
Raul Albiol, Faouzi Ghoulam and Amadou Diawara are rested in favour of Vlad Chiriches, Ivan Strinic and Jorginho, while Piotr Zielinski returns in place of Allan.
The Sardinians have the worst defensive record in the division, conceding 32 goals in 15 games, but lost only once at home in a 5-3 thriller with Fiorentina.
Roma came away from the Stadio Sant’Elia with a 2-2 draw, but other than that it was all Cagliari success stories.
David Di Gennaro is suspended following his red card in the stalemate at Pescara, while Luca Bittante, Nicola Murru, Joao Pedro and Artur Ionita are injured.
Diego Farias is only fit enough for the bench, so Nicolò Barella moves into the trequartista role behind Marco Sau and Marco Borriello.
It is a particularly special game for Borriello and Fabio Pisacane, who are both from the Naples area.
Cagliari have not beaten Napoli, home or away, since a 2-0 result here in April 2009. That was followed by five draws and seven defeats.
Cagliari: Storari; Isla, Ceppitelli, Bruno Alves, Pisacane; Dessena, Tachtsidis, Padoin; Barella; Sau, Borriello
Cagliari bench: Rafael, Briukhov, Capuano, Salamon, Munari, Oliveira, Farias, Melchiorri, Giannetti
Napoli: Reina; Hysaj, Chiriches, Koulibaly, Strinic; Zielinski, Jorginho, Hamsik; Callejon, Mertens, Insigne
Napoli bench: Rafael, Sepe, Giaccherini, Allan, Maggio, Maksimovic, Gabbiadini, Rog, Ghoulam, Albiol, Diawara, El Kaddouri