Now five Premier League games have been called off this weekend due to the COVID outbreak, while Chelsea and Liverpool reported positive tests, including former Inter striker Romelu Lukaku.
While Serie A remains relatively unaffected by the wave of Coronavirus making its way through sport, the Premier League is decimated.
There are now five fixtures planned for this weekend that have been postponed due to the lack of players available amid COVID outbreaks.
The matches called off after Manchester United-Brighton, Southampton-Brentford, Watford-Crystal Palace, West Ham-Norwich and Everton-Leicester.
It comes after Leicester City-Tottenham was called off last night just over two hours before it was due to kick off.
Serie A COVID vaccine uptake protecting from Premier League cancellations
This evening, Liverpool and Chelsea announced they had new cases too, as Fabinho, Curtis Jones and Virgil van Dijk tested positive, while Lukaku, Timo Werner, Callum Hudson-Odoi and Ben Chilwell were all out for the Blues.
Questions surely must be asked about the level of vaccination in the Premier League, especially after a report emerged from the EFL showing that 25 per cent of its players had no intention of getting vaccinated.
While there have been a few cases in Serie A in recent weeks, they were relatively isolated and asymptomatic.
The remarkable thing about the Premier League situation is how much the spread goes straight through the squad.
Manchester United alone had 19 positive tests between players and members of staff.