Roma have a 1-0 lead going into the Europa League semi-final with Bayer Leverkusen, as Paulo Dybala is on the bench, so Tammy Abraham and Andrea Belotti lead the way.
It kicks off at the BayArena at 20.00 UK time (19.00 GMT).
The first leg ended 1-0 thanks to a goal from youth product Edoardo Bove, but as the away goals rule is scrapped, that means any defeat by a one-goal margin here would force extra time.
Jose Mourinho’s injury list remains extensive, missing Marash Kumbulla and Rick Karsdorp, while Dybala, Chris Smalling and Stephan El Shaarawy are only fit for a spot on the bench.
Bryan Cristante again has to fill in for the back three.
Bayer Leverkusen dropped down from the Champions League into this tournament, just like the other semi-finalists Juventus and Sevilla.
Patrik Schick is out against his former club, alongside Robert Andrich and Odilon Kossounou, who sustained serious injuries at the Stadio Olimpico.
Surprisingly, Sardar Azmoun starts rather than Adam Hlozek.
Bayer Leverkusen: Hradecky; Tapsoba, Tah, Hincapié; Frimpong, Demirbay, Palacios, Bakker; Diaby, Wirtz; Azmoun
Roma: Rui Patricio; Mancini, Cristante, Ibanez; Celik, Bove, Matic, Spinazzola; Pellegrini; Belotti, Abraham
Ref: Vincic (SVN)
Player statistic
Piero Hincapié | 45+3' |
Exequiel Palacios | 56' | |||
Mitchel Bakker | 70' | |||
71' | Roger Ibañez | |||
89' | Bryan Cristante | |||
Moussa Diaby | 90' | |||
Edmond Tapsoba | 90+7' | |||
90+9' | Tammy Abraham |