Napoli coach Luciano Spalletti is short of options ahead of the big game against Napoli in the Europa League, but he has managed to make some changes from the last league match.
The Partenopei need a win against Leicester to be sure of a place in the next round of the Europa League, as only two points separate the first and fourth in Group C.
But Napoli are going through a difficult moment due to injuries and Spalletti must keep one eye on the title battle in Serie A too, as the Azzurri have only won one in their last five games across all competitions.
Napoli are without Kalidou Koulibaly, Victor Osimhen, Zambo Anguissa, Fabian Ruiz, Stanislav Lobotka and captain Lorenzo Insigne.
The coach is expected to give Dries Mertens a breather and Andrea Petagna seems set to start up front in a 4-2-3-1 formation.
Matteo Politano, Hirving Lozano and Eljif Elmas are expected to start in the attacking trident behind the former SPAL forward.
Giovanni Di Lorenzo, Amir Rrahmani, Juan Jesus and Mario Rui seem set to start in defence, ahead of Alex Meret in goal.
Probable line-ups: Napoli vs. Leicester
Napoli (4-2-3-1): Meret; Di Lorenzo, Rrahmani, Juan Jesus, Mario Rui; Demme, Zielinski; Politano, Lozano, Elmas; Petagna
Leicester (4-2-3-1): Schmeichel; Castagne, Evans, Soyuncu, Thomas; Tielemans, Ndidi; Albrighton, Maddison, Barnes; Vardy