Ciro Immobile returns from injury to lead out Lazio in the Europa League trip to Lokomotiv Moscow, supported by Felipe Anderson and Mattia Zaccagni.
It kicks off at 17.45 in Moscow and you can follow the build-up and action as it happens from that game and Roma-Zorya on the LIVEBLOG.
The Biancocelesti have had middling results in the Europa League so far this season, with one win, two draws and one defeat.
Their only victory so far was against Lokomotiv in Rome, but avoiding defeat here will be enough to ensure a place in the Round of 16.
Immobile has missed several games through a calf injury and returns to lead the line with Felipe Anderson and Zaccagni.
Sergej Milinkovic-Savic, Danilo Cataldi and Pepe Reina are all rested, giving Lucas Leiva and Toma Basic a start.
Lokomotiv need a victory to keep their hopes alive, so opt for a more attacking than usual formation, although Rifat Zhemaletdinov is out of action.
Former Roma defender Tin Jevaj starts in the back four, with Anton Miranchuk the twin brother of Atalanta midfielder Aleksei out injured.
Lokomotiv Moscow: Khudiakov; Nenakhov, Jedvaj, Murilo, Rybus; Maradishvili, Barinov, Beka Beka; Rybchinskii, Lisakovich, Kamano
Lokomotiv Moscow bench: Savin, Pablo, Smolov, Silyanov, Borisenko, Petrov, Cherny, Babkin, Khylnov, Zinovich
Lazio: Strakosha; Patric, Luiz Felipe, Acerbi, Hysaj; Luis Alberto, Leiva, Basic; Felipe Anderson, Immobile, Zaccagni
Lazio bench: Reina, Moretti, Escalante, Akpa-Akpro, Pedro, Romero, Milinkovic-Savic, Radu, Moro, Lazzari, Cataldi, Muriqi