Milan take no chances with Slavia Praha in the Europa League Round of 16, starting Rafael Leao, Christian Pulisic and Olivier Giroud.
It kicks off at the Eden Arena in Prague at 17.45 GMT.
You can follow all the build-up and action as it happens from this game, Fiorentina-Maccabi Haifa, Atalanta-Sporting and Brighton-Roma on the LIVEBLOG.
The Rossoneri won the first leg 4-2, but that was a struggle considering El Hadji Malick Diouf was sent off after just 26 minutes for a studs-up tackle on Pulisic’s ankle.
Alessandro Florenzi is suspended, with Tommaso Pobega injured, but Fikayo Tomori made his comeback from the start at the weekend and plays again here.
Stefano Pioli fields a full-strength squad, including Rafael Leao, Ruben Loftus-Cheek, Pulisic and Giroud.
The only surprise is Yunus Musah for Tijjani Reijnders in midfield.
Slavia Praha obviously have Diouf suspended following his red card, but Christos Zafeiris, Petr Sevcik and Lukas Masopust are not at 100 per cent, with Ivan Schranz also carrying a knock.
In the circumstances, it was suggested that Tomas Holes could be moved from defence into midfield to plug the gaps.
Slavia Praha topped their Europa League group ahead of Roma, largely due to a 2-0 win here.
It has been a tense few days for Milan, whose offices were raided as part of an investigation into the sale of the club from Elliott Management to RedBird in 2022.
However, there is also reason to celebrate, as Milan beat Real Madrid on penalties to reach the UEFA Youth League Final Four.
Slavia Praha: Stanek; Vlceck, Ogbu, Zima, Zmrzly; Holes, Dorley; Doudera, Provod, Wallem; Chytil
Milan: Maignan; Calabria, Tomori, Gabbia, Theo Hernandez; Adli, Musah; Pulisic, Loftus-Cheek, Leao; Giroud
Ref: Nyberg (SWE)
Player statistic
Tomas Holes | 20' | |||
David Douděra | 22' | |||
33' | Christian Pulisic (Assist: Rafael Leão) | |||
36' | Ruben Loftus-Cheek (Assist: Theo Hernández) | |||
44' | Fikayo Tomori | |||
45+6' | Rafael Leão (Assist: Christian Pulisic) |
56' | Matteo Gabbia | |||
Matej Jurasek (Assist: Christos Zafeiris) |
84' | |||
Michal Tomic | 86' | |||
Oscar Dorley | 89' | |||
89' | Rafael Leão |