Roma have Nicolò Zaniolo back with Andrea Belotti and Lorenzo Pellegrini as they try to get off the mark in the Europa League with HJK Helsinki.
It kicks off at the Stadio Olimpico at 20.00 UK time (19.00 GMT).
You can follow all the build-up and action as it happens from this game, Midtjylland-Lazio and Istanbul Basaksehir-Fiorentina on the LIVEBLOG.
The Giallorossi won the Conference League last season, but this term hasn’t started on the right foot, suffering a surprise 2-1 defeat away to Ludogorets.
They were also hammered 4-0 in Serie A by Udinese and only just scraped a 2-1 win at Empoli over the weekend.
Zaniolo returns after almost a month out with a dislocated shoulder, but Paulo Dybala and Tammy Abraham are rested, while Rick Karsdorp is also available again.
HJK Helsinki began their campaign with a 2-0 home defeat to Real Betis.
Valtteri Moren, Manuel Martic and Roope Riski are out of action, but former Chievo and Benevento player Perparim Hetemaj is in midfield.
Roma: Rui Patricio; Ibanez, Mancini, Vina; Karsdorp, Cristante, Matic, Spinazzola; Zaniolo, Pellegrini; Belotti
HJK Helsinki: Hazard; Raitala, Tenho, Hoskonen; Browne, Lingman, Väänänen, Hetemaj; Hostikka, Abubakari, Soiri