Juventus need a victory away to FC Nantes and opt for Moise Kean supported by Angel Di Maria, initially benching Dusan Vlahovic, in the Europa League Round of 16 play-off.
It kicks off at 17.45 GMT and the first leg ended 1-1 in Turin, but away goals no longer count double.
The Bianconeri will go to extra time if it ends in a stalemate after 90 minutes, so need a victory to progress into the Europa League after dropping down from the Champions League.
Federico Chiesa, Paul Pogba, Arkadiusz Milik and Fabio Miretti are out injured, so the trident attack is shelved for a 3-5-1-1 with Di Maria supporting Kean rather than Vlahovic.
Nantes see this as one of the greatest games in their European history and therefore have absolutely nothing to lose.
Florent Mollet comes in for Samuel Moutoussamy with last week’s scorer Ludovic Blas also supporting Andy Delort.
Quentin Merlin is still out injured, but Ignatius Ganago returns to the squad after missing the first leg on compassionate leave following the tragic death of his daughter.
Nantes: Lafont; Castelletto, Girotto, Pallois; Centonze, Sissoko, Chirivella, Simon; Blas, Mollet; Delort
Juventus: Szczesny; Danilo, Bremer, Alex Sandro; De Sciglio, Fagioli, Locatelli, Rabiot, Kostic; Di Maria; Kean
Player statistic
| 5' |  |
Ángel Di María (Assist: Nicolò Fagioli) | ||
| Nicolas Pallois |  |
17' | ||
| 20' |  |
Ángel Di María |
| 78' | |
Ángel Di María (Assist: Dusan Vlahovic) | ||
| Charles Traoré |  |
81' | ||
| 87' | |
Juan Cuadrado | ||
| Alban Lafont | |
90+4' |
Match statistic
