Lazio stick with Ciro Immobile and Luis Alberto in their Europa League trip to Denmark against Midtjylland, aiming to maintain the 100 per cent record.
It kicks off in Herning at 17.45 UK time (16.45 GMT).
The Biancocelesti were leading Feyenoord 4-0 before taking their foot off the gas for an eventual 4-2 result.
Maurizio Sarri as always is no big fan of squad rotation, but is missing injured Mattia Zaccagni and Manuel Lazzari.
Sergej Milinkovic-Savic is rested, with Pedro joining Immobile and Felipe Anderson upfront.
Midtjylland have won only two of their 14 competitive matches so far this season and lost the Europa League opener 1-0 to Sturm Graz.
Pablo Ortiz and Junior Brumado are not fully fit, but Anders Dreyer is one to watch, though Pione Sisto is benched.
Midtjylland: Lossl; Tychosen, Sviatchenko, Dalsgaard, Paulinho; Olsson, Martinez, Evander; Isaksen, Kaba, Dreyer
Lazio: Provedel; Hysaj, Mario Gila, Romagnoli, Radu; Vecino, Cataldi, Luis Alberto; Felipe Anderson, Immobile, Pedro