Lazio begin their Europa League campaign against last season’s Conference League Finalists Feyenoord, starting Ciro Immobile, Luis Alberto and Felipe Anderson.
It kicks off at the Stadio Olimpico at 20.00 UK time (19.00 GMT).
This group is completed by Sturm Graz and Midtjylland.
The Biancocelesti are still smarting after their controversial Serie A defeat to Napoli, but Maurizio Sarri keeps squad rotation to a minimum.
It had been assumed that goalkeeper Luis Maximiano would return after he was sent off six minutes into his debut for handling outside the box, but instead Ivan Provedel again keeps the gloves.
Sergej Milinkovic-Savic is rested, but the usual suspects start with Immobile, Mattia Zaccagni, Felipe Anderson and Luis Alberto.
Danilo Cataldi can play, as he is suspended against Verona this weekend.
Feyenoord lost the Conference League Final to Roma last season and have started this term in the Eredivisie with four wins and a draw.
Lutsharel Geertruida is injured.
Lazio: Provedel; Hysaj, Mario Gila, Romagnoli, Marusic; Vecino, Cataldi, Luis Alberto; Felipe Anderson, Immobile, Zaccagni
Feyenoord: Bijlow; Pedersen, Trauner, Hancko, Hartman; Q Timber, Orkun Kocku, Szymanski; Walemark, Danilo Pereira, Dilrosun