Roma must win away to HJK Helsinki to keep their Europa League dreams alive, but make some surprising changes on this artificial pitch.
It kicks off in Helsinki at 20.00 UK time (19.00 GMT).
The Giallorossi are trailing in this group in third place on four points, behind Ludogorets on seven and Real Betis with 10.
They must win to set up the final showdown with the Bulgarians at the Stadio Olimpico, otherwise face accepting third and drop into the Conference League play-offs.
Nicolò Zaniolo continues the three-match ban after his red card for a petulant kick off the ball against Betis, with Roger Ibanez, Nemanja Matic, Paulo Dybala, Zeki Celik and Georginio Wijnaldum all injured.
Lorenzo Pellegrini starts despite not being 100 per cent fit, but Stephan El Shaarawy and Cristian Volpato play in what could be a 4-3-3 or a 3-4-2-1 with Matias Vina in defence.
Jose Mourinho has already complained about the playing surface in Finland, insisting that it is “a different sport” on a synthetic turf and remembering their previous defeats in Norway against Bodo/Glimt.
HJK Helsinki are bottom of the group and are missing Valtteri Moren, Roope Riski and suspended Jukka Raitala, but have former Chievo man Perparim Hetemaj in midfield.
HJK Helsinki: Hazard; Hoskonen, Halme, Peltola; Soiri, Lingman, Vaananen, P Hetemaj, Browne; Hostikka, Olusanya
Roma: Rui Patricio; Vina, Mancini, Smalling, Zalewski; Pellegrini, Cristante, Camara; El Shaarawy, Abraham, Volpato
Ref: Tiago Martins (POR)