Atalanta must beat Sporting CP to reach the Europa League quarter-finals, as they look to Gianluca Scamacca, Ademola Lookman and Aleksei Miranchuk.
It kicks off at the Gewiss Stadium in Bergamo at 20.00 GMT.
The first leg ended 1-1 in Lisbon with La Dea rattling the frame of the goal three times, so with no away goals rule, it is winner takes all here.
These sides also met in the group stage, with Atalanta winning 2-1 away and drawing 1-1 at home earlier this season.
Gian Piero Gasperini’s men hit a dire period of form recently, without a win in five competitive games, drawing 2-2 with Juventus on Sunday.
Teun Koopmeiners scored twice, but he he rested in favour of Aleksei Miranchuk, supporting Lookman and Scamacca, while Isak Hien steps into defence.
Sporting CP adopt a very similar tactical approach to Atalanta, but are missing midfielder Hidemasa Morita due to fever, plus long-term absentee Antonio Adan.
Atalanta: Musso; Djimsiti, Hien, Kolasinac; Holm, De Roon, Ederson, Bakker; Miranchuk; Lookman, Scamacca
Sporting CP: Israel; St. Juste, Diomande, Gonçalo Inacio, Esgaio, Hjulmand, Goncalves, Reis; Edwards, Gyokeres, Trincao
Ref: Schärer (SUI)
Player statistic
| 33' |  |
Pedro Gonçalves (Assist: Viktor Gyökeres) |
| Ademola Lookman (Assist: Aleksey Miranchuk) |
|
46' | ||
| Gianluca Scamacca (Assist: Aleksey Miranchuk) |
|
59' | ||
| Emil Holm |  |
78' |
Match statistic
