Italy are completely revamped against Malta, with Giacomo Bonaventura, Domenico Berardi, Giacomo Raspadori and Moise Kean upfront.
It kicks off at the Stadio San Nicola in Bari at 19.45 UK time (18.45 GMT).
You can follow all the build-up and action as it happens on the LIVEBLOG.
The Azzurri are decimated with injuries to Ciro Immobile, Federico Chiesa, Mattia Zaccagni, Mateo Retegui, Lorenzo Pellegrini, Matteo Politano and Ivan Provedel.
Sandro Tonali and Nicolò Zaniolo were also sent home after they were placed under formal investigation for illegal betting.
It means an all-new trident attack with Berardi, Raspadori and Kean, while Fiorentina veteran Bonaventura makes his first appearance since October 2020.
Malta have captain Steve Borg suspended, with Teddy Teuma, Jodi Jones and Shaun Dimech injured.
Italy: Donnarumma; Darmian, Mancini, Bastoni, Dimarco; Barella, Locatelli, Bonaventura; Berardi, Raspadori, Kean
Italy bench: Vicario, Meret, Di Lorenzo, Biraghi, Udogie, Scamacca, Acerbi, Cristante, Frattesi, Scalvini, Orsolini, El Shaarawy
Malta: Bonello; Apap, Pepe, Z Muscat; J Mbong, Kristensen, Guillaumier, Yankam, Camenzuli; P Mbong, Montebello
Malta bench: Al-Tumi, Galea, Attard, J Borg, Shaw, S Pisani, Degabriele, Paiber, Satariano, Corbolan, Nwoko, N Muscat
Ref: Strukan (CRO)
Player statistic
Giacomo Bonaventura | 23' | |||
44' | Paul Mbong | |||
Domenico Berardi (Assist: Nicolò Barella) |
45+1' |
53' | Yannick Yankam | |||
54' | Ferdinando Apap | |||
Domenico Berardi (Assist: Moise Kean) |
63' | |||
Davide Frattesi | 90+3' |