Italy field the expected XI in their Euro 2020 opener, with Domenico Berardi and Manuel Locatelli stepping in, while Turkey rely on Hakan Calhanoglu and Burak Yilmaz.
It kicks off at the Stadio Olimpico at 20.00 UK time (19.00 GMT).
You can follow all the build-up and action as it happens and give your views on the LIVEBLOG.
This is the opening game of the entire tournament and also of Group A, which also includes Switzerland and Wales.
The Azzurri lost Stefano Sensi and Lorenzo Pellegrini, who pulled out of the competition due to muscular injuries, while Marco Verratti has not yet recovered from a knee issue.
As expected, Roberto Mancini sticks with the same XI that beat the Czech Republic 4-0 in a friendly last week.
That means Alessandro Florenzi and Leonardo Spinazzola as the full-backs, Locatelli stepping into midfield and Berardi rather than Federico Chiesa in a trident attack with Ciro Immobile and Lorenzo Insigne.
Turkey are very dangerous on the counter-attack and hope to defend well before quick turnovers.
There were suggestions that Sassuolo defender Kaan Ayhan would move into midfield as extra protection, partnering West Bromwich Albion’s Okay Yokuslu.
Instead, it’s a more traditional choice with Ozan Tufan.
Milan midfielder Hakan Calhanoglu pulls the strings behind striker Burak Yilmaz.
There is another Serie A representative in the form of Juventus defender Merih Demiral, while Cengiz Under is on the bench.
Turkey: U Cakir; Celik, Demiral, Soyuncu, Meras; Karaman, Tufan, Yokuslu, Yazici, Calhanoglu; Yilmaz
Turkey bench: Gunok, Bayindir, Under, Tokoz, Antalyali, Kabak, Unal, Kokcu, Can Kahveci, Ayhan, Muldur, Dervisoglu
Italy: G Donnarumma; Florenzi, Bonucci, Chiellini, Spinazzola; Barella, Jorginho, Locatelli; Berardi, Immobile, Insigne
Italy bench: Sirigu, Meret, Di Lorenzo, Belotti, Pessina, Emerson, Chiesa, Acerbi, Cristante, Bernardeschi, Raspadori, Bastoni
Ref: Makkelie (NED)