Italy rely on Marco Verratti in midfield for the Euro 2020 Round of 16 against Austria, with Francesco Acerbi and Giovanni Di Lorenzo stepping in.
It kicks off at Wembley Stadium at 20.00 UK time (19.00 GMT).
You can follow all the build-up and action as it happens and give your views on the LIVEBLOG.
The Azzurri can make history, as they are unbeaten in an all-time record-equalling 30 games and have kept 11 consecutive clean sheets.
Roberto Mancini had to choose between Verratti and Manuel Locatelli for the midfield, and has plumped for the PSG star.
Giorgio Chiellini and Alessandro Florenzi are not fully fit, so Acerbi and Di Lorenzo come in to fill the gaps.
Austria are in the Euros Round of 16 for the first time and hadn’t gone beyond the group stage in a major tournament since 1982.
Marko Arnautovic is on the verge of a transfer to Bologna and he leads the attack in quite a defensive set-up, with David Alaba at left-back.
Florian Grillitsch protects the back four and will try to neutralise Jorginho, while Martin Hinteregger has shaken off a knock.
Italy: Donnarumma; Di Lorenzo, Acerbi, Bonucci, Spinazzola; Barella, Jorginho, Verratti; Berardi, Immobile, Insigne
Italy bench: Sirigu, Meret, Locatelli, Belotti, Pessina, Emerson, Chiesa, Cristante, Bernardeschi, Raspadori, Bastoni, Toloi
Austria: Bachmann; Lainer, Hinteregger, Dragovic, Alaba; Grillitsch; Laimer, X Schlager, Sabitzer, Baumgartner; Arnautovic
Austria bench: A Schlager, Pervan, Ulmer, Posch, Ilsanker, Gregoritsch, Baumgartlinger, Lienhart, Trimmel, Schaub, Schopf, Kalajdzic
Ref: Taylor (ENG)