Inter rely on Lautaro Martinez, Alexis Sanchez and Arturo Vidal for the Coppa Italia semi-final, while Juventus have Dejan Kulusevski with Cristiano Ronaldo.
The first leg kicks off at San Siro at 19.45 GMT, with the return in Turin on February 9.
You can follow all the build-up and action as it happens and give your views on the LIVEBLOG.
Inter rely on Lautaro Martinez, Alexis Sanchez and Arturo Vidal for the Coppa Italia semi-final, while Juventus have Dejan Kulusevski with Cristiano Ronaldo.
The first leg kicks off at San Siro at 19.45 GMT, with the return in Turin on February 9.
You can follow all the build-up and action as it happens and give your views on the LIVEBLOG.
The Nerazzurri are forced to do without suspended Romelu Lukaku and Achraf Hakimi, who accumulated enough yellow cards in the tournament to trigger a ban.
They were both booked in the stormy 2-1 quarter-final win over Milan, so Alexis Sanchez steps in as the partner to Lautaro Martinez.
Christian Eriksen returns to the bench, with Marcelo Brozovic, Vidal and Nicolò Barella running the midfield.
Hakimi is replaced by Matteo Darmian, with Ashley Young chosen for the left flank.
Juventus have Paulo Dybala and Aaron Ramsey out injured, but Giorgio Chiellini and Leonardo Bonucci are both rested for Matthijs de Ligt with Merih Demiral.
Alex Sandro gets his first start since recovering from COVID, but Federico Chiesa is benched with Alvaro Morata.
Dejan Kulusevski is instead chosen alongside Ronaldo, with 43-year-old Gigi Buffon in goal.
These teams met only 16 days ago, with Inter winning the Serie A edition of the Derby d’Italia 2-0 here.
Inter: Handanovic; Skriniar, De Vrij, Bastoni; Darmian, Barella, Brozovic, Vidal, Young; Lautaro Martinez, Alexis Sanchez
Inter bench: Padelli, Radu, Gagliardini, Vecino, Kolarov, Sensi, Ranocchia, Perisic, Eriksen, D’Ambrosio, Pinamonti
Juventus: Buffon; Cuadrado, Demiral, De Ligt, Alex Sandro; McKennie, Bentancur, Rabiot, Bernardeschi, Ronaldo, Kulusevski
Juventus bench: Szczesny, Pinsoglio, Chiellini, Danilo, Bonucci, Dragusin, Frabotta, Arthur, Chiesa, Fagioli, Peeters, Morata
Ref: Calvarese