Fiorentina rely on Luis Muriel and Federico Chiesa, while Papu Gomez returns with Duvan Zapata and Josip Ilicic for Atalanta in the Coppa Italia semi-final.
The first leg kicks off at the Stadio Franchi at 20.00 GMT.
You can follow the build-up and action as it happens and give your views on the LIVEBLOG.
Fiorentina rely on Luis Muriel and Federico Chiesa, while Papu Gomez returns with Duvan Zapata and Josip Ilicic for Atalanta in the Coppa Italia semi-final.
The first leg kicks off at the Stadio Franchi at 20.00 GMT.
You can follow the build-up and action as it happens and give your views on the LIVEBLOG.
These sides did not expect to be in the semi-final for the Coppa Italia and one of them will face Lazio or Milan in the showdown for the trophy in May.
The Viola humiliated Roma 7-1 in the quarter-final, while the Bergamo boys knocked holders Juventus out with a 3-0 result.
Fiorentina rested Muriel for the 3-3 thriller with Inter and the Colombian returns to the starting XI with Chiesa and Gerson, moving Giovanni Simeone to the bench.
German Pezzella and Kevin Mirallas are out injured.
Atalanta have Berat Djimsiti and Remo Freuler suspended for the first leg, while Robin Gosens is injured.
Captain and star forward Alejandro ‘Papu’ Gomez returns to the side after missing the 2-0 Serie A defeat to Torino.
Ex-Fiorentina man Ilicic also supports Duvan Zapata, with Mario Pasalic stepping in to the midfield.
Fiorentina: Lafont; Milenkovic, Ceccherini, Hugo, Biraghi; Dabo, Benassi, Veretout; Chiesa, Gerson; Muriel
Fiorentina bench: Terracciano, Brancolini, Pezzella, Fernandes, Laurini, Hancko, Norgaard, Simeone, Pjaca, Graiciar, Vlahovic, Montiel
Atalanta: Berisha; Toloi, Palomino, Mancini; Hateboer, De Roon, Pasalic, Castagne; Gomez; Ilicic, Duvan Zapata
Atalanta bench: Gollini, Rossi, Masiello, Ibanez, Reca, Pessina, Kulusevski, Piccoli, Barrow
Ref: Giacomelli