Coppa Italia: Napoli vs. Cagliari - Confirmed line-ups

Antonio Conte has made eight changes to his Napoli side for this evening’s Coppa Italia round of 16 match against Cagliari, as he prepares to take on his former club, Juventus, in Serie A over the weekend.

Kick-off is due at 17.00 GMT (18.00 CET).

You can follow the action as it unfolds on the Football Italia Liveblog.

NAPLES, ITALY - NOVEMBER 25: Antonio Conte SSC Napoli head coach before the UEFA Champions League 2025/26 League Phase MD5 match between SSC Napoli and Qarabag FK at Stadio Diego Armando Maradona on November 25, 2025 in Naples, Italy. (Photo by Francesco Pecoraro/Getty Images) — NAPLES, ITALY – NOVEMBER 25: Antonio Conte before the UEFA Champions League 2025/26 League Phase MD5 match against Qarabag FK at Stadio Diego Armando Maradona on November 25, 2025 in Naples, Italy. (Photo by Francesco Pecoraro/Getty Images)

This is Napoli’s first involvement in the Coppa Italia this season, while the visitors have already defeated Virtus Entella and Frosinone in the earlier rounds of the cup in order to qualify for this evening’s round of 16 tie.

Conte already has one eye on Sunday’s Serie A headliner against his former club Juventus, and has therefore decided to name a heavily rotated side against Cagliari on Wednesday.

Of the team that started in Napoli’s 1-0 win over previous league leaders Roma on Sunday, only Vanja Milinlovic-Savic, Sam Beukema and Mathias Olivera keep their place in the starting line-up. Amir Rrahmani, Alessandro Buongiorno, Giovanni Di Lorenzo, Stanislav Lobotka, Scott McTominay, David Neres, Rasmus Hojlund and Noa Lang have all been rested.

ROME, ITALY - NOVEMBER 30: Amir Rrahmani, Sam Beukema and Scott McTominay of Napoli celebrates victory following the Serie A match between AS Roma and SSC Napoli at Stadio Olimpico on November 30, 2025 in Rome, Italy. (Photo by Paolo Bruno/Getty Images) — ROME, ITALY – NOVEMBER 30: Amir Rrahmani, Sam Beukema and Scott McTominay of Napoli celebrates victory following the Serie A match between AS Roma and SSC Napoli at Stadio Olimpico on November 30, 2025 in Rome, Italy. (Photo by Paolo Bruno/Getty Images)

Luca Marianucci is suspended and therefore unavailable, but it is expected that he would have also started had he been available.

Napoli are still without Romelu Lukaku, Kevin De Bruyne, Andre-Frank Zambo Anguissa and Billy Gilmour.

This means that there are opportunities for some of Napoli’s lesser-seen first-team squad members, including 22-year-olds Antonio Vergara, Giuseppe Ambrosino and Pasquale Mazzocchi.

Cagliari, who were beaten 2-1 by Juventus over the weekend, have also made several alterations to their starting line-up, but there are opportunities for the likes of Zito Luvumbo, Gianluca Gaetano and Leonardo Pavoletti in the starting line-up against Napoli.