Roma coach José Mourinho will look to Tammy Abraham and Nicolò Zaniolo in the first leg of the Conference League Round of 16.
It kicks off at 17.45 at the Stadium Gelredome, with around 1,100 Roma fans in the stands.
Leonardo Spinazzola is the only player out of action for Roma. There are a few doubts in defence and midfield for the Special One with Rick Karsdorp favourite over Ainsley Maitland-Niles, while Sergio Oliveira should get the nod over Bryan Cristante.
Abraham and Zaniolo will start in attack. The ex-Chelsea striker has scored 20 goals across all competitions this season, six in the Conference League. Roma are the best team in the last seven games in Serie A (with Juventus), having collected 15 points in the process. However, they’ve lost six games away from home in Serie A this term (six wins and one draw).
Vitesse vs. Roma, probable line-ups
Vitesse (3-4-1-2): Houwen; Oroz, Rasmussen, Doekhi; Dasa, Tronstad, Bero, Wittek; Domgjoni; Frederikksen, Openda.
Roma (3-4-1-2): Rui Patricio; Mancini, Smalling, Kumbulla; KArsdorp, Oliveira, Mkhitaryan, Vina; Pellegrini; Zaniolo, Abraham.