Fiorentina badly need a result in Scotland to get their Conference League campaign kick-started, so look to Luka Jovic against Hearts.
It kicks off at Tynecastle Park in Edinburgh at 20.00 UK time (19.00 GMT).
The Viola have had a dismal campaign so far, largely caused by their inability to convert chances into goals, and go into this game bottom of Group A with just one point.
Coach Vincenzo Italiano is without Antonin Barak, Gaetano Castrovilli and Riccardo Sottil, but the pressure is on Jovic to deliver, flanked by Riccardo Saponara and Christian Kouame.
Hearts lost 4-0 at home to Istanbul Basaksehir and then won 2-0 away to RFS Riga, while they were beaten 4-0 here by Rangers at the weekend.
Craig Halkett, Kye Rowles and Liam Boyce are injured, with Robert Snodgrass off the Europa League list, but Barrie McKay and Stephen Kingsley are available despite knocks.
Hearts: Gordon; M Smith, L Neilson, Kingsley, Cochrane; Grant, Kiomourtzoglou, Halliday; Ginnelly, Shankland, McKay
Fiorentina: Gollini; Terzic, Martinez Quarta, Igor, Biraghi; Bonaventura, Amrabat, Mandragora; Kouame, Jovic, Saponara
Ref: Lambrechts (BEL)