Fiorentina can secure their place in the Conference League knockouts with a victory against Genk, so rely on Nico Gonzalez and Christian Kouame.
It kicks off at the Stadio Franchi at 20.00 GMT.
The Viola are top of their group on eight points, followed by Ferencvaros and Genk on six.
Giacomo Bonaventura has a muscular issue and Rolando Mandragora is suffering from flu symptoms, so they join Dodo and Gaetano Castrovilli on the absentee list.
Michael Kayode returns after spraining his ankle on October 26, while Kouame gets the nod rather than Lucas Beltran or M’Bala Nzola upfront.
When these sides met in Belgium on September 21, Fiorentina twice fumbled a lead for the 2-2 draw.
Genk have a full squad available and the form man is right-back Daniel Muñoz, who has found the net in his last three games.
Fiorentina: Christensen; Parisi, Martinez-Quarta, Mina, Biraghi; Maxime Lopez, Duncan; Nico Gonzalez, Barak, Ikone; Kouame
Genk: Von Crombrugge; Munoz, Cuesta, Sadick, Kayembe; Heynen, Galarza, Hrosovsky; Paintsil, Arokodare, Fadera
Ref: Kooj (NED)
Player statistic
| 20' |  |
Alieu Fadera | ||
| Lucas Martínez Quarta | |
28' | ||
| Lucas Martínez Quarta |  |
45+4' | ||
| 45' | |
Joris Kayembe (Assist: Christopher Bonsu Baah) |
| Nicólas González |  |
79' | ||
| 81' | |
Daniel Muñoz | ||
| 89' | |
Joseph Paintsil | ||
| 89' | |
Patrik Hrosovsky | ||
| Nikola Milenkovic | |
90+2' | ||
| Cristiano Biraghi | |
90+7' | ||
| Christian Kouamé | |
90+7' | ||
| 90+2' | |
Andi Zeqiri | ||
| 90+4' | |
Matías Galarza | ||
| 90+6' | |
Carlos Cuesta |
Match statistic
