Federico Chiesa and Federico Bernardeschi are back in the Juventus squad, but are not expected to start, while questions remain around Milan goalkeeper Mike Maignan’s injury.
It kicks off at 19.45 UK time (18.45 GMT).
Max Allegri has Chiesa and Bernardeschi back in the squad after they missed the Napoli and Malmo matches through injury.
Mattia De Sciglio also returns to the fold, though Arthur Melo and Kaio Jorge are still sidelined.
They are nonetheless not expected to start this evening, as they are still not 100 per cent fit.
Milan made the trip without six players, Zlatan Ibrahimovic, Olivier Giroud, Rade Krunic, Tiemoue Bakayoko, Davide Calabria and Junior Messias.
Goalkeeper Maignan is in the group, but his presence at the Allianz Juventus Stadium remains in doubt.
He sustained a bruise to the left wrist while saving Mohamed Salah’s penalty in the Champions League trip to Liverpool.
If the Frenchman doesn’t make it, then Ciprian Tatarusanu will take over the gloves.
There are also suggestions Fikayo Tomori will be re-routed as a right-back rather than Alessandro Florenzi, who is again not at 100 per cent.
Juventus (4-4-2): Szczesny; Danilo, De Ligt, Chiellini, Alex Sandro; Cuadrado, Bentancur, Locatelli, Rabiot; Dybala, Morata
Milan (4-2-3-1): Maignan; Tomori, Kjaer, Romagnoli, Theo Hernandez; Kessié, Tonali; Saelemaekers, Brahim Diaz, Leao; Rebic
— JuventusFC (@juventusfcen) September 19, 2021
📜 Our squad travelling to Turin for #JuveMilan
— AC Milan (@acmilan) September 19, 2021