Milan seem set to start with Ante Rebic, Ismael Bennacer and Alessio Romagnoli against Atletico Madrid in the Champions League tonight.
The match at San Siro kicks off at 20.00 UK time.
After the return to the competition ended in a defeat against Liverpool, Milan face another tough game in the second round of Group B.
Atletico Madrid arrive at San Siro and the Spanish champions were the team that eliminated Milan during their last appearance in the Champions League in 2013-14.
Simon Kjaer, Sandro Tonali and Olivier Giroud seem set to miss out against Atleti, but they still have one more training session to re-claim a place in the side.
But the Rossoneri coach is expected to make changes, with Romagnoli next to Fikayo Tomori in defence and Bennacer in the middle over Tonali.
Rebic should get the nod up front, supported by Alexis Saelemaekers, Brahim Diaz and Rafael Leao.
Argentine coach Diego Simeone has some problems too and is expected to arrive in a 4-4-2 formation.
Felipe should replace Stefan Savic in the heart of the defence, while Kieran Trippier and Mario Hermoso are expected on the sides.
Rodrigo de Paul returns to Italy after his move from Udinese, while Thomas Lemar and Joao Feliz return. Antoine Griezmann and Luis Suarez should be in attack.
Probable line-ups: Milan vs. Atletico Madrid
Milan (4-2-3-1): Maignan; Calabria, Tomori, Romagnoli, Theo Hernandez; Kessie, Bennacer; Saelemaekers, Brahim Diaz, Leao; Rebic
Atletico Madrid (4-4-2): Oblak; Trippier, Felipe, Gimenez, Hermoso; Correa, De Paul, M. Llorente, Carrasco; Griezmann, Suarez