Luciano Spalletti only has two doubts ahead of tonight’s match against Eintracht Frankfurt, which could send the Azzurri to the Champions League quarter-finals for the first time ever.
It kicks off at 20.00 GMT at the Stadio Maradona.
The Serie A leaders won 2-0 in Germany in February.
Giacomo Raspadori is the only player out of action for the hosts, while Alex Meret, Kim and Hirving Lozano are back.
Spalletti only has two doubts: Mario Rui or Matias Olivera at left-back, Lozano or Matteo Politano on the right wing.
Napoli have scored at least three goals in each home Champions League match this season but have never qualified for the quarter-finals in history. They are also unbeaten in the last 11 Champions League matches played at home, with eight wins and three draws.
Victor Osimhen and Khvicha Kvaratskhelia will start up front. With four Champions League assists this season, Georgia international has already set a record for a Napoli player in the competition. He has also created 16 goal-scoring opportunities, more than any other teammate.
Eintracht have travelled to Napoli without Éric Junior Dina Ebimbe and Jesper Lindstrøm while Randal Kolo Muani was sent off in the reverse fixture and is suspended. Eintracht fans are not allowed inside the Stadio Maradona tonight due to security reasons.
Napoli-Eintracht: probable line-ups
Napoli (4-3-3): Meret; Di Lorenzo, Rrahmani, Kim, Mario Rui; Anguissa, Lobotka, Zielinski; Politano, Osimhen, Kvaratskhelia.
Eintracht Frankfurt (3-4-2-1): Trapp; Tuta, Jakic, Ndicka; Knauff, Rode, Sow, Max; Gotze, Kamada; Borré.