They kick off at 20.00 UK time (19.00 GMT).
The Bianconeri had a dismal start to the season under returning coach Max Allegri with one point from three rounds, so hope to begin their European campaign in a very different vein with this trip to Swedish side Malmo.
They are in a group with Chelsea and Zenit St Petersburg.
Atalanta haven’t done much better and are missing Luis Muriel for their match with Unai Emery’s Europa League holders Villarreal.
La Dea share a group with Manchester United and Young Boys.