Atalanta look to Duvan Zapata, Mario Pasalic and Ruslan Malinovskyi as they look for their second Champions League win of the season against Swiss outfit Young Boys.
It kicks off at the Wankdorf Stadium in Berne at 20.00 GMT.
La Dea are in their third ever Champions League participation and aim to reach the knockouts for the third time running.
So far, they have just one victory – 1-0 over YB in Bergamo – two draws and a last-gasp 3-2 defeat to Manchester United.
Robin Gosens and Hans Hateboer are joined on the treatment table by Matteo Lovato, but Rafael Toloi is back in business for the defence.
Malinovskyi and Pasalic get the nod ahead of Josip Ilicic to support Duvan Zapata, with Luis Muriel ready to come off the bench.
Young Boys started their Champions League campaign with a 2-1 win over 10-man Manchester United, but it’s been all downhill after that.
Injuries haven’t helped, as they are missing Christian Fassnacht, goalkeeper David von Ballmoos, Mohamed Ali Camara, Cedric Zesiger, Jean-Pierre Nsame and Joel Monteiro.
Their home stadium uses an artificial turf.
Young Boys: Faivre; Hefti, Burgy, Lauper, Garcia; Martins Pereira, Aebischer, Rieder, Ngamaleu; Siebatcheu, Elia
Young Boys bench: Zbinden, Spielmann, Sierro, Kanga, Sulejmani, Jankewitz, Mambimbi, Maier, Maceiras, Lefort, Lustenberger, Toure
Atalanta: Musso; Toloi, Demiral, Palomino; Zappacosta, De Roon, Freuler, Maehle; Pasalic, Malinovskyi; Duvan Zapata
Atalanta bench: Rossi, Sportiello, Koopmeiners, Muriel, Pezzella, Djimsiti, Pessina, Scalvini, Miranchuk, Ilicic, Piccoli
Ref: Siebert (GER)