Milan look to Olivier Giroud, Brahim Diaz and Sandro Tonali in their must-win Champions League match with FC Porto.
It kicks off at San Siro at 17.45 GMT, you can follow all the build-up and action as it happens from this game and Sheriff-Inter on the LIVEBLOG.
The Rossoneri have so far lost all three of their Champions League group games, although with some bad luck and controversy.
Their chances of qualification are slim, especially after losing 1-0 in Portugal, but there is a boost with the return of Brahim Diaz for the first time since contracting COVID-19.
He starts in support of Giroud, while Tonali runs the midfield with Ismael Bennacer, leaving Franck Kessie on the bench with Simon Kjaer ahead of the Milan Derby.
Fode Ballo-Toure joined Mike Maignan, Ante Rebic, Alessio Romagnoli, Junior Messias and Alessandro Plizzari on the treatment table.
Porto are forced to make changes from the side that won 1-0, as Wendell and Ivan Marcano are out of action, but Matheus Uribe surprisingly recovers to start.
Milan will be unable to finish in the top two if they lose to Porto, or if they draw and Atletico Madrid beat Liverpool.
The Rossoneri will be confirmed in fourth place, and out of contention for a UEFA Europa League berth, if they lose and Atletico win.
Milan: Tatarusanu; Calabria, Tomori, Romagnoli, Theo Hernandez; Tonali, Bennacer; Saelemaekers, Brahim Diaz, Leao; Giroud
Milan bench: Mirante, Jungdal, Ibrahimovic, Kalulu, Kjaer, Maldini, Krunic, Bakayoko, Gabbia, Kessie
Porto: Diogo Costa; Joao Mario, Mbemba, Pepe, Zaidu; Otavio, Sergio Oliveira, Uribe, Luis Diaz; Taremi, Evanilson
Porto bench: Marchesín, Fábio Cardoso, Pepê, Grujic, Tecatito, Manafá, Bruno Costa, Toni Martínez, Nanu, Francisco Conceição, Vitinha, Fábio Vieira
Ref: Turpin (FRA)