Inter make radical changes for their Champions League showdown with Sadio Mane’s Bayern Munich, including Andre Onana’s debut in goal and Henrikh Mkhitaryan in midfield.
It kicks off at San Siro at 20.00 UK time (19.00 GMT).
The Nerazzurri have already lost twice this season in Serie A to Lazio and Milan, so Simone Inzaghi is under pressure to turn things around.
He’s in the Group of Death with Barcelona and Viktoria Plzen, so needs a strong start in this competition.
Romelu Lukaku is injured, so Edin Dzeko steps in for Joaquin Correa as partner to Lautaro Martinez.
Nicolò Barella and Samir Handanovic are surprisingly dropped in favour of Henrikh Mkhitaryan and debutant goalkeeper Andre Onana, who has not played a competitive match since April at Ajax.
It is the first time Mkhitaryan and Hakan Calhanoglu have started together.
Bayern Munich have drawn their last two Bundesliga matches by 1-1 scorelines, as they are starting to miss Robert Lewandowski following his move to Barcelona.
Former Juventus defender Matthijs de Ligt starts with Thomas Muller and Kingsley Coman supporting Leroy Sané and Sadio Mané.
Inter: Onana; D’Ambrosio, Skriniar, Bastoni; Dumfries, Mkhitaryan, Brozovic, Calhanoglu, Gosens; Dzeko, Lautaro Martinez
Inter bench: Handanovic, Cordaz, Gagliardini, De Vrij, Correa, Bellanova, Asllani, Acerbi, Barella, Dimarco, Darmian
Bayern Munich: Neuer; Pavard, De Ligt, Lucas Hernandez, Davies; Kimmich, Sabitzer; Coman, Muller, Sané; Mané
Bayern Munich bench: Ulreich, Schenk, Upamecano, Gnabry, Goretzka, Choupo-Moting, Gravenberch, Tel, Mazraoui, Musiala, Stanisic