Tommaso Pobega and Yunus Musah are expected to start in Milan‘s midfield against Borussia Dortmund tonight with Malick Thiaw returning to the starting XI.
It kicks off at 20:00 BST.
The Rossoneri picked up a 0-0 draw in the first group stage game against Newcastle two weeks ago, while the Germans lost to PSG.
Ruben Loftus-Cheek is injured and Yacine Adli will rest after starting in two consecutive matches, so Pobega and Musah will get the nod in the middle of the park alongside Tijjani Reijnders.
Pierre Kalulu is injured too, so Thiaw will join Fikayo Tomori in central defence after resting in the last Serie A game against Lazio.
No changes in attack with Rafael Leao, Olivier Giroud and Christian Pulisic who will reunite with his ex-club.
The American winger scored 19 goals in 127 appearances with the Bundesliga side before joining Chelsea in 2019.
Former Juventus midfielder Emre Can is expected to start in central midfield for the Germans.
Borussia Dortmund-Milan, probable line-ups
Borussia Dortmund (3-5-2): Kobel; Sule, Hummels, Schlotterbeck; Ryerson, Sabitzer, Emre Can, Brandt, Wolf; Adeyemi, Malen.
Milan (4-3-3): Maignan; Calabria, Thiaw, Tomori, Theo Hernandez; Musah, Reijnders, Pobega; Pulisic, Giroud, Leao.